Formulate & Innovate with Dairy Ingredients

Formulate & Innovate with Dairy Ingredients

Getting to know each dairy ingredient by its composition is the first step in understanding its performance and matching the right ingredient with the target food application.

Formulate & Innovate with Dairy Ingredients

Getting to know each dairy ingredient by its composition is the first step in understanding its performance and matching the right ingredient with the target food application.

Formulating with Dairy Ingredients

Proteins

Dairy protein composition can be the biggest differentiator between ingredients because there are two distinct groups of proteins in milk: caseins and whey proteins.  Dairy ingredients are comprised of ingredients with a range of protein levels from zero to over 90%. The products that contain protein may have only caseins or whey proteins or varying combinations of caseins and whey proteins.

Caseins and whey proteins are very different in their structure and function but the best part of these differences are that if one doesn’t work, then it is likely that the other one will.  For instance, caseins are quite heat-stable, so they have a multitude of applications in products that undergo heat treatment (e.g., shelf-stable low-acid (pH 6.5-7) beverages).  On the other hand, whey proteins are stable in acidic conditions, so they remain soluble and clear in low pH (pH < 3.5) beverages (though caseins would precipitate).  Micellar casein and caseinates are more effective at water-binding, while whey protein concentrates have superior foaming properties, egg-replacement and fat-replacement capabilities.

Carbs, Bioactives & Probiotics

Lactose is not the only carbohydrate in milk. Cow colostrum and cow milk contain approximately 1.57 g and between 200 and 300 mg of oligosaccharides per liter, respectively… (1). Oligosaccharides are composed of three to twenty monosaccharides. Also known as sialyloligosaccharides, oligosaccharides are important bioactive compounds that contribute to immunity and brain development in infants. In infants and adults, cow milk oligosaccharides act as prebiotics, promote the growth of beneficial bacteria in the gastrointestinal tract, which subsequently produce short chain fatty acids, lower the pH of the gut, and make it difficult for pathogens to colonize the gut (2). 
 
Weinborn et al. (2020) (3) effectively isolated oligosaccharides from whey permeate and modified them by the addition of fucose and/or sialic acid to generate human milk oligosaccharide-like glycans that can be used to improve infant formula functionality.

Milkfats

Fat has traditionally been one of the most valuable components in milk.  The fat in milk is primarily in the form of triacylglycerols (~90% triglycerides), but also di- and mono-glycerides, fatty acids, sterols, carotenoids, and vitamins A, D, E and K. Milk fat is dispersed in milk serum (skim) in small droplets, or globules, composed of a membrane that contains bioactive proteins, phospholipids and other components.  Milk fat globules help maintain an “oil-in-water” emulsion. The oil in water emulsion of cream is intentionally disrupted into the “water-in-oil” emulsion known as butter.
 

Milk fats provide flavor, nutrition and functionality.  Fat-rich dairy ingredients include Anhydrous milkfat (99.8% min), Butteroil (99.3% min), Butter (80% min), whole milk powder (WMP, 26% min), and whey protein phospholipid concentrate (WPPC 12% min).

Milk fat contains predominantly saturated fatty acids, along with some mono-unsaturated and poly-unsaturated fatty acids.  The Dietary Guidelines for Americans continue to recommend consumption of low fat and fat free dairy products, and limitation of saturated fats to <10% of daily calories.  However, a multitude of research has shown that all dairy products, even full-fat dairy foods, are associated with positive health outcomes.  Here are some recent examples from peer reviewed literature.

  • Dairy foods and dairy fat consumption are associated with reduced prevalence of type 2 diabetes and hypertension (4)
  • Dairy foods–regardless of the fat content–are associated with reduced risk of metabolic syndrome (4)
  • A diet comprised of higher amounts of fruit, vegetables, nuts, legumes, fish, and whole-fat dairy is associated with lower CVD and mortality in all world regions, especially in countries with lower income where consumption of these foods is low (5).
  • Cheese consumption was found to be inversely associated with all-cause mortality cardiovascular mortality, incident cardiovascular disease (CVD) , coronary heart disease (CHD), stroke, estrogen receptor-negative (ER-) breast cancer, type 2 diabetes, total fracture, and dementia (6). 

Bioactives Compounds

Dairy ingredients are rich in bioactive compounds, including the casein glycomacropeptide, oligosaccharides, alpha-lactalbumin, lactoferrin, osteopontin, and milk fat globule membrane components.  Not only do bioactives provide nutrition, but they also have biological functional properties such as bone homeostasis improvement, mineral absorption promotion, immune regulation, antioxidant properties, antimicrobial action, and intestinal health improvement. 

Bioactive peptides derived from milk, eggs, fish and marine byproducts have been shown to regulate adipogenesis, lipid metabolism, and appetite control, suggesting promise for obesity prevention and management applications (7).

Lactic acid bacteria used to produce fermented dairy products are able to produce a variety of bioactive compounds during fermentation, including bioactive peptides, bacteriocins, and vitamins (8). 

Addition of bioactive milk components to infant formula and functional foods has improved quality of life and contributed to healthy aging (9).  

Dairy Ingredient Application Guides

Using resources like the ADPI Composition, Functionality and Application Guides, food product developers can select the best ingredient for their application and be more successful in their formulation journey.

Meet ADPI Members who are Making it with Dairy!

References:
(1) Durham, SD, Z Wei, DG Lemay, MC Lange and D Barile.  2023.  Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals.  Scientific Reports.  13:  https://doi.org/10.1038/s41598-023-36866-y
 
(2) Lovallo, C, C Marchitelli, F Napolitano, S Claps, and A Crisa.  2022.  Sialyloligosaccharides content in mature milk of different cow breeds.  Sustainability.  14(5): 2805.  https://doi.org/10.3390/su14052805
 

(3) Weinborn, V.; Li, Y.; Shah, I.M.; Yu, H.; Dallas, D.C.; German, J.B.; Mills, D.A.; Chen, X.; Barile, D. Production of functional mimics of human milk oligosaccharides by enzymatic glycosylation of bovine milk oligosaccharides. Int. Dairy J. 2020, 102, 104583.

(4) Bhavadharini, B, M Dehghan, A Mente, S Rangarajan, P Sheridan, Viswanathan Mohan, Romaina Iqbal, R Gupta, S Lear, E Wentzel-Viljoen, A Avezum, P Lopez-Jaramillo, P Mony, R P Varma, R Kumar, J Chifamba, K F Alhabib, N Mohammadifard, A Oguz, F Lanas, D Rozanska, K B Bostrom, K Yusoff, L P Tsolkile, A Dans, A Yusufali, A Orlandini, P Poirier, R Khatib, B Hu, L Wei, L Yin, A Deeraili, K Yeates, R Yusuf, N Ismail, D Mozaffarian, K Teo, S S Anand, S Yusuf. 2020. Association of dairy consumption with metabolic syndrome, hypertension and diabetes in 147 812 individuals from 21 countries. BMJ Open Diabetes Res Care. 8(1):e000826. doi: 10.1136/bmjdrc-2019-000826

(5) Mente, A, M Dehghan, S Rangarajan, M O’Donnell, W Hu, G Dagenais, A Wielgosz, S A. Lear, L Wei, R Diaz, A Avezum, P Lopez-Jaramillo, F Lanas, S Swaminathan, M Kaur, K Vijayakumar, V Mohan, R Gupta, A Szuba, R Iqbal, R Yusuf, N Mohammadifard, R Khatib, N M Nasir, K Karsidag, A Rosengren, A Yusufali, E Wentzel-Viljoen, J Chifamba, A Dans, K F Alhabib, K Yeates, K Teo, H C Gerstein, S Yusuf. 2023. Diet, cardiovascular disease, and mortality in 80 countries, European Heart Journal, Volume 44, Issue 28, 21 July 2023, Pages 2560–2579, https://doi.org/10.1093/eurheartj/ehad269

(6) Mingjie Zhang, Xiaocong Dong, Zihui Huang, Xue Li, Yue Zhao, Yingyao Wang, Huilian Zhu, Aiping Fang, Edward L. Giovannucci. 2023. Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies. Advances in Nutrition, 14(5):1170-1186

(7) Suryaningtyas, IT and JY Je.  2023.  Trends in Food Sci Tech.  138: 141-152.
 

(8) Sorensen, HM, KD Rochfort, S Maye, G Macleod, C Loscher, D Brabazon, and B Freeland.  2023.  Nutrients.  15(22): https://doi.org/10.3390/nu15224754 

(9) Mao, X-Y, L-H Han, Q-C Yuan, H Gong, X Y Mao, L H Han, Q C Yuan, and H Gong.  2022.  J. Food Sci. Tech.  40(2): 15-24.

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